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Index > Protein center > Col2a1(Gene name) > Rat
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  • Col2a1 (Gene name),
  • Collagen alpha-1(II) chain (Protein name ),  CO2A1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Col2a1;
    Protein name:
    Collagen alpha-1(II) chain;
    Alternative:
    Alpha-1 type II collagen;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homotrimers of alpha 1(II) chains.
    Function:
    Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    1419
    Sequence:
    50:
    MIRLGAPQSL | VLLTLLIATV | LQCQGQDARK | LGPKGQKGEP | GDIKDIIGPK | 
    100:
    GPPGPQGPAG | EQGPRGDRGD | KGERGAPGPR | GRDGEPGTPG | NPGPPGPPGP | 
    150:
    PGPPGLGGGN | FAAQMAGGFD | EKAGGAQMGV | MQGPMGPMGP | RGPPGPAGAP | 
    200:
    GPQGFQGNPG | EPGEPGVSGP | IGPRGPPGPA | GKPGDDGEAG | KPGKAGERGL | 
    250:
    PGPQGARGFP | GTPGLPGVKG | HRGYPGLDGA | KGEAGAPGVK | GESGSPGENG | 
    300:
    SPGPMGPRGL | PGERGRTGPA | GAAGARGNDG | QPGPAGPPGP | VGPAGGPGFL | 
    350:
    GAPGAKGEAG | PTGARGPEGA | QGSRGEPGNP | GSPGPAGASG | NPGTDGIPGA | 
    400:
    KGSAGAPGIA | GAPGFPGPRG | PPGPQGATGP | LGPKGQTGEP | GIAGFKGEQG | 
    450:
    PKGETGPAGP | QGAPGPAGEE | GKRGARGEPG | GAGPIGPPGE | RGAPGNRGFP | 
    500:
    GQDGLAGPKG | APGERGPSGL | AGPKGANGDP | GRPGEPGLPG | ARGLTGRPGD | 
    550:
    AGPQGKVGPS | GAPGEDGRPG | PPGPQGARGQ | PGVMGFPGPK | GANGEPGKAG | 
    600:
    EKGLAGAPGL | RGLPGKDGET | GAAGPPGPSG | PAGERGEQGA | PGPSGFQGLP | 
    650:
    GPPGPPGEGG | KQGDQGIPGE | AGAPGLVGPR | GERGFPGERG | SPGAQGLQGP | 
    700:
    RGLPGTPGTD | GPKGAAGPDG | PPGAQGPPGL | QGMPGERGAA | GIAGPKGDRG | 
    750:
    DVGEKGPEGA | PGKDGGRGLT | GPIGPPGPAG | ANGEKGEVGP | PGPSGSTGAR | 
    800:
    GAPGERGETG | PPGPAGFAGP | PGADGQPGAK | GDQGEAGQKG | DAGAPGPQGP | 
    850:
    SGAPGPQGPT | GVTGPKGARG | AQGPPGATGF | PGAAGRVGPP | GSNGNPGPAG | 
    900:
    PPGPAGKDGP | KGARGDTGAP | GRAGDPGLQG | PAGAPGEKGE | PGDDGPSGSD | 
    950:
    GPPGPQGLAG | QRGIVGLPGQ | RGERGFPGLP | GPSGEPGKQG | APGASGDRGP | 
    1000:
    PGPVGPPGLT | GPAGEPGREG | SPGADGPPGR | DGAAGVKGDR | GETGALGAPG | 
    1050:
    APGPPGSPGP | AGPTGKQGDR | GEAGAQGPMG | PSGPAGARGI | AGPQGPRGDK | 
    1100:
    GEAGEPGERG | LKGHRGFTGL | QGLPGPPGPS | GDQGTSGPAG | PSGPRGPPGP | 
    1150:
    VGPSGKDGSN | GIPGPIGPPG | PRGRSGETGP | AGPPGNPGPP | GPPGPPGPGI | 
    1200:
    DMSAFAGLGQ | REKGPDPLQY | MRADEADSTL | RQHDVEVDAT | LKSLNNQIES | 
    1250:
    IRSPDGSRKN | PARTCQDLKL | CHPEWKSGDY | WIDPNQGCTL | DAMKVFCNME | 
    1300:
    TGESCVYPNP | ATVPRKNWWS | SKSKEKKHIW | FGETMNGGFH | FSYGDGNLAP | 
    1350:
    NTANVQMTFL | RLLSTEGSQN | ITYHCKNSIA | YLDEAAGNLK | KALLIQGSND | 
    1400:
    VEMRAEGNSR | FTYTALKDGC | TKHTGKWGKT | IIEYRSQKTS | RLPIVDIAPM | 
    1419:
    DIGGPDQEFG | VDIGPVCFL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Collagen alpha-1(II) chain
    Cat.:
    E0572r
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    96T
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    ELISA Kit for Rat Collagen alpha-1(II) chain
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    E0572h
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    96T
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    ELISA Kit for Rat Collagen alpha-1(II) chain
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    E0572m
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    Packing:
    96T
    ELISA Kit for Rat Collagen alpha-1(II) chain
    Cat.:
    E0572b
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    Packing:
    96T
    ELISA Kit for Rat Collagen alpha-1(II) chain
    Cat.:
    E0572c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Collagen alpha-1(II) chain
    Cat.:
    U0572c
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Collagen alpha-1(II) chain
    Cat.:
    U0572h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Collagen alpha-1(II) chain
    Cat.:
    U0572m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Collagen alpha-1(II) chain
    Cat.:
    U0572b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Collagen alpha-1(II) chain
    Cat.:
    U0572r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Rat Collagen alpha-1(II) chain
    Cat.:
    P0572Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Collagen alpha-1(II) chain
    Cat.:
    P0572Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Collagen alpha-1(II) chain
    Polyclonal Antibody for Rat Collagen alpha-1(II) chain
    Polyclonal Antibody for Rat Collagen alpha-1(II) chain
    Cat.:
    P0572Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Collagen alpha-1(II) chain
    Monoclonal Antibody for Rat Collagen alpha-1(II) chain
    Monoclonal Antibody for Rat Collagen alpha-1(II) chain
    Monoclonal Antibody for Rat Collagen alpha-1(II) chain
    Monoclonal Antibody for Rat Collagen alpha-1(II) chain
    Protein for Rat Collagen alpha-1(II) chain
    Protein for Rat Collagen alpha-1(II) chain
    Protein for Rat Collagen alpha-1(II) chain
    Cat.:
    R0572h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Rat Collagen alpha-1(II) chain
    Protein for Rat Collagen alpha-1(II) chain

    R&D Technical Data
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    12% SDS-PAGE analysis

          12% SDS-PAGE analysis

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Complete rat type II collagen cDNA sequence."
      Urabe K. , Sarkar G. , Bolander M.E.
      Submitted (1995-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Bone.
    2. 2.
      "Isolation and characterization of a cDNA clone for the amino-terminal portion of the pro-alpha 1(II) chain of cartilage collagen."
      Kohno K. , Martin G.R. , Yamada Y.
      J. Biol. Chem.259:13668-13673(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-122
    3. 3.
      "Structure of the promoter of the rat type II procollagen gene."
      Kohno K. , Sullivan M. , Yamada Y.
      J. Biol. Chem.260:4441-4447(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-29
    4. 4.
      "T-cell recognition of carbohydrates on type II collagen."
      Michaelson E. , Malmstrom V. , Reis S. , Engstrom A. , Burkhardt H. , Holmdahl R.
      J. Exp. Med.180:745-749(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 370-422
      strain: DA.
      tissue: Cartilage.
    5. 5.
      "A role for prolyl 3-hydroxylase 2 in post-translational modification of fibril-forming collagens."
      Fernandes R.J. , Farnand A.W. , Traeger G.R. , Weis M.A. , Eyre D.R.
      J. Biol. Chem.286:30662-30669(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HYDROXYLATION AT PRO-602; PRO-839; PRO-1076; PRO-1118; PRO-1133; PRO-1139 AND PRO-1145;TISSUE SPECIFICITY;IDENTIFICATION BY MASS SPECTROMETRY
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